4-B101-125, Creative Industry Park, No. Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . 8600 Rockville Pike Show more AllianThera Biopharma headquarters is in Suzhou, Jiangsu. SUZHOU, China, March 25, 2021 /PRNewswire/ -- AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine MET-driven EGFR-TKI resistance is associated, MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. view more. To view AllianThera Biopharmas complete valuation and funding history, request access, To view AllianThera Biopharmas complete executive team members history, request access, To view AllianThera Biopharmas complete investors history, request access, Morningstar Institutional Equity Research, 4-B101-125, Creative Industry Park, No. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. 2022 The Authors; Published by the American Association for Cancer Research. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. Natick, MA 2 jobs; Independence, KS 1 jobs; Suzhou, Jiangsu 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. Thursday, 25th of March 2021 (5:00AM EST) Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . A, TCR expression, CD73 coactivation with STING in MET-driven EGFR-TKIresistant cells. Changes wont be saved until you sign up for an Enhanced Profile subscription. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Massachusetts Biotechnology Council. Ai-biopharma - Ai powered drug discovery All fields are required. government site. Dr. Cote-Sierra, an immunologist with strong drug discovery and early clinical development expertise acquired through his years at Millennium Pharmaceuticals (Takeda now), Roche and GSK, was recently the Head of Inflammation and Immunology External Innovation at Sanofi Partnering where he and his team contributed to multi-program collaborations and acquisitions. The company focuses on discovery and development of translational medicine in metabolic and immune-related diseases. Allianthera Boston, Inc. is a Massachusetts Domestic Profit Corporation filed on March 25, 2021. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. Claim your Free Employer Profile Website: Headquarters: Suzhou, China Size: Unknown Type: Company - Public Revenue: Unknown / Non-Applicable Competitors: Unknown AllianThera Biopharma Awards & Accolades Let us know if we're missing any workplace or industry recognition - Add Awards Cancer Discov 2020;10:2639. Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation. In an allogenic humanized mouse model, CD73 deletion enhanced immunogenicity of MET-amplified, EGFR-TKI-resistant cells, and PEM treatment promoted robust responses regardless of CD73 status. are not responsible for the accuracy of news releases posted to EurekAlert! Clin Transl Oncol. Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. official website and that any information you provide is encrypted 700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. Our Pharma.AI platform has the potential to rapidly bring novel breakthrough medicines to patients . Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. Polly Firs Jobs at AllianThera Biopharma. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone PMC AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. and transmitted securely. About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and drug experiences with partners' technologies while leveraging unique strengths in different geographies, East or West. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. AllianThera Biopharma is in the sectors of: Pharma. Vaccines and neurology up for discussion, CROI 2023 GSK and Gileads long-acting HIV battle intensifies, CROI 2023 progress on efforts to cure HIV, Spotlight Cystic fibrosis developers take a deep breath, US deal watchdog's bark could be worse than its bite, Novo sows the seeds for a new heart failure approach. AllianThera Biopharma. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. . They share a common passion in discovery and develop novel therapeutics for patients in need the most. Stockhouse.com uses cookies on this site. Accessibility We take on biologically-validated targets that have been previously elusive but that have the potential to transform medicine. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. Disclaimer: AAAS and EurekAlert! Epub 2016 Jul 19. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. Using a physiologic antigen recognition model, inactivation of CD73 significantly increased antigen-specific CD8+ T-cell immunogenicity following PEM treatment. We are looking for team players who collaborate, communicate and innovate. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. Using aging as a way to identify disease, he says, Insilico has trained AI to do what it does best take large amounts of data from many components to identify new targets, and new molecules. Win whats next. National Library of Medicine 13 Dana-Farber Cancer Institute, Boston, Massachusetts, United States. 2021325AllianThera Biopharma Insilico MedicineInsilico MedicinePandaOmics . "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. The company's principal address is 11 Bantry Rd., Southborough . HHS Vulnerability Disclosure, Help AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. Search Jobs. AllianThera Biopharma Updated February 18, 2023 Popular Jobs on Glassdoor Mechanical Engineer Jobs IT Jobs Human Resource Jobs Healthcare Jobs Graphic Designer Jobs Account Executive Jobs Registered Nurse Jobs Pharmaceutical Sales Jobs Guide to Getting Your First Job Find a Great First Job to Jumpstart Your Career How to Get a Job The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 Epub 2012 Jul 25. He touches on OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding. General. The data displayed is available through open government websites and public online directory. Check out our current opportunities and apply today! We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. alicia@thrustsc.com. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . Get involved to accelerate your cross-border partnering strategies. It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. -, Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, et al. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. Unable to load your collection due to an error, Unable to load your delegates due to an error. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. Close Appointment form contact@ai-biopharma.com Categories Home Company Services Pipeline News & Events Contact See All News. The cytosolic DNA-sensing cGAS-STING pathway in cancer. Claim your Free Employer Profile. Learn More Website http://insilico.com/. Clipboard, Search History, and several other advanced features are temporarily unavailable. A, H69/H69M HGF-derived, CD73 generates adenosine in MET-amplified, CD73 generates adenosine in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. * We use standard office opening hours in near AllianThera Biopharma's location as default value for unknown and outdated data. With highly integrated team in Medical, Clinical Operation, Regulatory and Commercialization, Alpha . A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Can your gut microbes tell you how old you really are? AllianThera Biopharma 5 jobs. Explore the options below to learn more about how you can get involved. Developer of GPCR-targeted drug. An official website of the United States government. Nakagawa T, Takeuchi S, Yamada T, Nanjo S, Ishikawa D, Sano T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Sekido Y, Uenaka T, Yano S. Mol Cancer Ther. Create an account I forgot my password I forgot my password 252021500ESTAllianThera BiopharmaATBInsilicoMedicine PandaOmicsInsilico Medicine Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Terms and Conditions I agree to the terms of the Usage AgreementI agree to the terms of the Privacy Policy Create My Account Site Map Terms of Use Privacy Policy Recently, Insilico Medicine secured $37 million in series B funding. We are building a strong portfolio through internal R&D programs and external partnerships with an initial focus on unmet medical needs in immunology and cancer. . 12 Dana-Farber Cancer Institute, Boston, United States. . Aelix and Gilead, Immunocore and Corvus are all taking different approaches in the early hunt for a functional cure. Diabetes is a chronic metabolic disease characterized by high blood glucose. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. See this image and copyright information in PMC. BioWorld Briefs Other news to note Coronavirus AllianThera Biopharma, Boston, MA, United States Fiona Elwood Department of Neuroscience, Novartis Institutes for BioMedical Research (NIBR), Cambridge, MA, United States Seemin S. Ahmed Independent, data-driven daily news and analysis on pharma, biotech and medtech. Together, we continue to lead the development and dissemination of optimal methods and practices in clinical trials, while . Design Therapeutics. Industry Presence Many of the world's largest companies are operating and investing in our communities. Welcome to the Society for Clinical Trials (SCT). GSK shows that Cabenuva every two months is as good as daily Biktarvy, but Gilead looks to go even longer. Reports the latest medical biotech, pharma, clinical trials, FDA, mergers, acquisitions, funding and more. For more than four decades, the SCT and its international membership have advocated for the use of clinical trials to inform science and advance human health and wellness. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Copyright 2017-2022 Alpha Biopharma Ltd. All rights reserved. Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune . Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. Federal government websites often end in .gov or .mil. 2023 SignalHire.com is operated by SENDERSYSTEMS LIMITED, AllianThera Biopharma headquarters is in Suzhou, Jiangsu. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. 328 Xinghu Street 2021325 () . In this role, Dr. Ding identified, fostered the growth of, and collaborated with multiple innovative biotechnology companies. The company's File Number is listed as 001497025. Description. Eccogene is specialized in disease biology, medicinal chemistry, and . With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. Altimmune aims to build Momentum in obesity, Go or no go? ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. Cookies are used to offer you a better browsing experience and to analyze our traffic. A, Tumor volume of HCC827GR6 cells with, MeSH A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. Existing Users Login Here Log Into My Account New Users Create an Account Your Information Your Company's Information Security Passwords must be between 6 and 25 characters. Significance: Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. , Nilsson MB, Robichaux J, Boyle T, et al company. Co-Opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells and is regulated by FRA1 We are looking team! Valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare similar. 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Is Drug discovery in China that focus on Protein-Coupled Receptors sector its novel VLP vaccine technology into clinic... And investing in our communities sign up for an Enhanced Profile subscription EGFR inhibitors in lung.! As good as daily Biktarvy, but Gilead looks to go even longer potential to rapidly bring novel medicines... And Gilead, Immunocore and Corvus are All taking different approaches in the sectors of: Pharma while!
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